Here's my setup.

Across my other alts, I already have enchanting, jc, tailoring, alchemy, engineering, leatherworking, skinning, mining, herb.
(Basically everything except Blacksmithing).

Here's my new 5-box team:
1x Paladin
3x Mages
1x Shaman

And this is what I'm thinking about choosing:

Paladin - Engineering (to help with pulling?), Mining
Mage A - Tailoring (nice Epics), Herb
Mage B - Tailoring (nice Epics), Skin
Mage C - Tailoring (nice Epics), Alchemy (for proc Mastery and Transmutes)
Shaman - LW (for the drums?), Enchanting (to DE BOP)

I have the 3 gathering because I hate seeing gold just laying there.
Alchemy because another proc mastery and transmutes a day is nice.
Tailoring for the mages seems to be a no-brainer
Enchanting, mostly just to DE the BOPs.

The 2 that I'm still iffy about is the Paladin (Engineering) and Shaman (LW).

For a Paladin, I've read that Engineering is the best way to pull with until we get Avenger's Shield (Lvl 50).

For the Shaman Resto, don't know which profession would be best. The best I came up with is LW. Although I don't see it helping until I get closer to 70 for the Drums. I honestly don't expect to get Primal Nethers, so I'm not really banking on the LW BOP Set.

If anyone has a better suggestion.