Synergy is benign. It can't script, bot, repeat, anything. People use it all the time. I use it to admin boxes. No concerns there.

AHK.... not as much. I doubt it would be a problem but it is hard to say because it could be used to script. I can elaborate more later but its a bit risky. I am pretty staunch about hardware only being the best but its expensive and there are cheaper methods that don't give up too much. I thought about going software only but there were too many downsides (for me and my goals). Perhaps running them all in virtual machines, so Warden can't know about AHK or the other WoW copies? Performance hits though.

4 copies of WoW on 1 machine is pushing it - quad core 4 gigs of memory and a 8800gtx with max settings? Sure. Single core, 1 gig, 6200 geforce? Hah.