I am guessing that by stipped you meant Stripped, which I will assume it is some level of raid.

I have a very similiar setup to yours, but my drives are not setup in any sort of raid. Basically C: and D:

OS (Vista 64) is on C: and WoWs with the symlinked datafolders are in D: and I think it is the main thing - you want to keep the OS separated from the WoW install.