I run on a LG 47" hooked up via HDMI to my PC (I have a HDMI <-> DVI cable I got somewhere online). I run 1920x1080 (or so) on the TV, and run my wow windows at 1360x768. Also have a 2nd 22" monitor hooked where I run a second window of WoW. It all works great, WoW looks gorgeous on a huge screen and its nice having browser windows on the side/behind since most of the grindy or instancy stuff in WoW is pretty boring.
No big pixel problems, no chunky graphics, everything is gorgeous and great. Make sure you get a 1080p TV, run it at 1920x1080 res. I usually have a TV show (daily show, etc) also running in a small window while playing, lol
There are some great deals on awesome 1080p 120hz 42" and higher TVs nowadays, definitely worth looking into.
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