I ran instances from level 12 all the way to level 70, never touched any quest's that didn't involve the instance I was grinding(skipped a # of those as well actually). I believe I hit 70 in about 9 days played and obviously had a good bit of practice doing difficult content so transitioning to heroics and bg's was relitively smooth ( aside from setting up a leaderless/focusless setup a few weeks later ). I made about the same money I would have expected to make doing quests via tradeskill drops ( enchanting mostly ).
Oxaz(4 shamans 1 pallie team, arena high of 1867, current 1802)/Thext(retired sort of)
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