I don't exactly understand the description but it sounds like a privilege problem. HotkeyNet can't see or inject keypresses on Vista if the active application is running at a higher privilege level.

I suggest running HotkeyNet as administrator on the Vista PC. If that doesn't fix it I'll ask you some questions so I can get a better idea of the problem.

Quote Originally Posted by 'Barman',index.php?page=Thread&postID=125892#post1 25892
Should this work or was this never tested with this OS. Or is it rather unlikely that this is an OS related issue?
Lots of people use HotkeyNet with 64 bit Vista. In fact I have 64 bit Vista myself.