One small question:

Are you clicking on the macro or hitting the corresponding key on the keyboard?

If you're clicking the macro it is not generating a keypress for keyclone to then broadcast to your other windows.

I ran into this last night while finally taking out my 4 baby shammies for a drive, I was using Vyndree's party1 assist macro but it wasn't working. Until I hit the 7 key (where the macro resided)