As i've posted in my OCZ Core SSD review, I'm going to start by saying that $550 videocard is gross overkill (you'll be running your LCD's refresh nearly 100% of the time, usually 60-72Hz = 60-72fps with that or a lesser card), and you're better off getting a $180 HD4850 and $199 OCZ Core 32GB SSD unless you're playing on a 30" 2560x1600 LCD. Also, there's no way I'd pick a dual-core over a quad-core with the same architecture for 5-boxing, even if I have to sacrifice a few MHz in core speed. Get a Q9450 (or Q6600) if you can.

Aside from that comment, the specs you listed will 5-box just fine.