Ok, I was able to fix 1 problem and 2 more crept up :cursing: . The 2 instance was not running at the same resolution. "Main" was at 1028x768 and "Two" was running at 800x600. I am now running both instance at 800x600. But I run into another problem. ?(
I am using the default actionbar from the game. Only the buttons closest to the middle is working, any button toward the edge of the screen do not work. ;(
My setting in Octopus for the Maximize is
Main(0,0,1200x1050)
Two(1200,0,480x525)
Three(1200,526,480x525)

2nd problem
I use a one button grind macro for both toon
/cast [btn:2] Siphon Life
/cast [mod:shift] Curse of Agony
/cast [mod:ctrl] Seed of Corruption
/cast [mod:alt] Drain Soul(Rank 1)
/castsequence reset=target Curse of the Elements,Siphon Life,Corruption,Life Tap,Drain Life,Shoot

When I hold down the alt, ctrl or shift button, the correct icon for the spell will showup on both instance but only the toon in the "main" will cast the spell. For Ex. I hold down the "Alt" key and the spell icon for "Drain Soul" will show on both instance but only the toon in "main" instance will cast the spell