if you haven't done it already, you should create keyclone commands ... not only does it help with start up and layout, but it also allows you to easily set the maxfpsbk and maxfps. if you don't, then all wows will attempt to get 999 fps... killing your fps.

while you are at it, you should also reduce your details (search the wiki for a few macros)

i'm running 5 wows on a single monitor getting 50fps each. i have 2x 260s in the box... each driving a different monitor... but if i put 4 on one and 1 on the other @ 1280x1024... i'm lucky to get 10/30 fps. i have been told it's the 750i mainboard which is having the problems (by design actually).