i responded to your pm.. but i'll post this here as well.

mouse-click-passing is not meant for constant game play. it's meant to be toggled on, do your limited clicks, then toggle off. in order for it to work, the mouse will have to jump around and activate each window in order for the game to process the click. click-n-drag will definitely not pass.

it is meant mostly for creating macros, interacting with quest givers, training and using vendors. you could try it with ground targeting.. but it would probably be sloppy due to the pov being off slightly for each character.