I've actually BEEN doing melee multiboxing in WoW for the first time just lately, with my shammy team.

Since I'm killing orange and reds, I decided there was no point blowing mana on spells that would be resisted in any case so I'm just bashing things to death, and it's working really well.

The AI is so poor that most things just stand there while I beat the living crap out of them.

There are a few methods for getting into melee combat, but I use this:

- Target mob, hit my assist button.
- Hit 'T' (default binding - start attack, could also just enable "attack on assist" in UI options).
- Run into the mob.

As soon as my drones get close enough to hit the mob, follow breaks automatically so they stand in exactly the right place. I then run my "main" through the mob, turn around and start bashing the back of his head in.

It'd never work in PvP, or in most instance encounters, but for grinding out quests it's been working surprisingly well