Curse of Weakness Question

Hi again :)
so with two locks, would it be worthwhile dropping in curse of weakness into the spell rotation for some bosses? I think curse of doom might be hard to manage for aggro but weakness might reduce melee targets enough to allow targets to go down faster and do less damage.
Any thoughts?

I wouldn't waste a curse with weakness, I'd just pop in Agony on the 2nd lock for the extra DPS.

Cool, exactly the input I needed :)