Incomiing huge noob question

Ive been playing around multiboxing on a computer but I want to broadcast mouse strokes so im stepping up to two monitors.

Now here is my question, do my monitors have to be hooked up somehow? Currently i have 2 computers, one is in another room while the main computer is in my room. Im familiar with AHK so I was wondering if I could multibox without having to move any hardware around. Do the monitors have to be externally connected to each other somehow?

I will add more noobish questions once this one gets answered in this thread, thank you! :P

There are a few applications which broadcast mouse movements but I would highly suggest against it. It will never be perfect and most likely be more frustration than actual gain.

Most actions can be achieved with macros and keybindings. The easiest mouse broadcasting solution (and one I use for ranged AoE) is a single mouse tuned to multiple receivers, but keybindings for most things is definitely the way to go.