When I was ratting in Nullsec, I found that a round-robin use of my F key for drones was really useful. I could lock 4-6 targets, and then cycle my F key one two three times per ship depending on the size, and everything died at once. Problem was locking time, I would want some scan res meds to keep up with locking more targets while killing the others. By the time you killed 4 targets, you want 4 more immediatly, and locking time on frigates is painful sometimes.